REACT

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Status

Closed

Design

Prospective, non-interventional, multicentre, Canadian practice assessment of adults with atherosclerotic cardiovascular disease (ASCVD) or familial hypercholesterolemia (FH)

Therapy Area
  • ASCVD
  • Lipid Management
Study Population

Adults with atherosclerotic cardiovascular disease (ASCVD) or familial hypercholesterolemia (FH)

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CIRT

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Status

Closed

Design

A randomized, double-blind, placebo-controlled, event-driven trial of weekly low-dose methotrexate (LDM) in the prevention of cardiovascular events among stable coronary artery disease patients with type 2 diabetes or metabolic syndrome.

Study Population

Patients with prior myocardial infarction or multi-vessel coronary disease who additionally had either type 2 diabetes or metabolic syndrome syndrome

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SPRINT-AF

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Status

Closed

Design

A prospective, non-interventional, multicentre, Canadian registry of Canadian adults with atrial fibrillation with two phases: a retrospective chart audit to assess current AF management, and a prospective observational registry.

Study Population

Adult participants with documented AF in the past 10 years

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PARADIGM

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Status

Closed

Design

A prospective, education-interventional, multicentre, Canadian registry of Canadian primary care physicians with two phases: a retrospective chart audit to determine current practice patterns for assessment of cardiovascular risk amongst primary care patients followed by a prospective practice assessment to determine practice change after completion of an educational intervention.

Study Population

Primary care participants

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