Jacques Genest

MD, FRCP(C)

Jacques Genest was born in Montréal, Canada. He obtained his MD at McGill University Medical School and did a residency in Internal Medicine at McGill then a cardiology fellowship at Tufts University New England Medical center in Boston. He did Post-doctoral studies in Boston in lipoprotein metabolism and molecular genetics at Tufts University. Since 2000, he is Professor of Medicine and holds the McGill/Novartis Chair in Medicine at McGill. From 2000-10, he was Head of Cardiology at McGill University. He is currently the Scientific Director of the Center for Innovative Medicine at the McGill University Health center (MUHC)

His research focuses on the metabolic and genetic basis of premature coronary artery disease and the role of high density lipoproteins (HDL) in atherosclerosis. His research team has contributed to the identification of several genes involved in the metabolism of HDL. His research funding comes from the Canadian Institutes of Health Research and the Heart and Stroke Foundation of Canada. He has been involved in designing and running several large clinical trials (HOPE-2, homocysteine; the JUPITER trial) and is a member of the steering committees of currently on-going trials ) CANTOS, REVEAL; Capree). He sits on several advisory boards for the pharmaceutical and biotechnology companies and is a reviewer for many scientific journals and granting agencies. He has published over 230 peer-reviewed manuscripts in journals such as Nature Genetics, Circulation, Circulation Research, New England Journal of Medicine, Journal of Biological Chemistry and The Lancet and has written 18 book chapters.

For the past 16 years, he has participated in the elaboration of Canadian Cholesterol Guidelines and has contributed the chapter on lipoprotein disorders and cardiovascular disease in the last 4 editions of Braunwald’s Textbook of Cardiovascular Disease, the major book in cardiovascular medicine.

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